The term "plain gut" is often related to a type of surgical suture material, while "PGA" stands for Polyglycolic Acid, another type of synthetic, absorbable suture material. They are not the same thing.
Plain Gut: This is a natural suture material made from purified collagen derived from the serosal layer of beef (bovine) intestines or the submucosal fibrous layer of sheep (ovine) intestines. Plain gut is absorbable and is broken down in the body by enzymatic degradation, which can take 70 days or less, depending on the patient's body. It is used in general soft tissue approximation and/or ligation, but its use is decreasing in favor of synthetic absorbable sutures due to its variable absorption rate and potential to cause significant inflammatory reaction in tissues.
PGA (Polyglycolic Acid): PGA sutures are synthetic, absorbable suture materials made from a polymer of glycolic acid. They are absorbed by the body through hydrolysis and are known for their predictable absorption rate, excellent tensile strength, and minimal tissue reaction. PGA sutures are widely used in many types of soft tissue approximation, including ophthalmic surgery, gynecological surgery, and the closure of internal soft tissues.
In summary, plain gut and PGA represent two different types of suture materials, with plain gut being natural and PGA being synthetic. Each has its own set of properties that make it suitable for specific types of surgical applications.